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Description

GP000005: HHV1-gB(50-56)-STn(53)C46H74N10O21 1103. 13 HHV1 gB(UniProt ID P08665) synthetic glycopeptide HSV1 gB fragment (Gly50 Pro56; UniProt position 50 56, aa length 7) from the N terminal region of Herpes Simplex Virus type 1 glycoprotein B. O glycosylation, Sialyl Tn (Neu5Ac2 6GalNAc O Thr) at position Thr53. The C terminus is an amide. The glycopeptide is known to bind Paired immunoglobulin like type 2 receptor alpha (PILR), and this association is involved in HSV 1 infection.

62 / An Fmoc-protected L-serine building block carrying a β-D-galactose residue

62 / An Fmoc-protected L-serine building block carrying an α-D-mannose residue

4-Carboxybutyl α-D-mannose 6-phosphate

TF-antigen

Sialyl Tn or STn (Neu5Acα2-6GalNAcα-O-Thr) at Thr139 and Thr144

The installed glycan is the sialyl-Tn antigen (Neu5Acα2-6GalNAcα-O-Ser/Thr)

TF Epitope (Serine)

/ Fmoc-Ser((Ac)3-Fuc-α-L)-OH / Fmoc-Ser(α-L-Fuc)-OH

H-Ser(α-D-GalNAc)-OH

27 / An α-D-N-acetylgalactosamine (α-D-GalNAc) ligand equipped with an azide-functionalized linker through a short ethyl spacer

5-(β-D-Glucopyranosyl-oxy) pentanoic acid

α2-6 sialosides are ligands for Siglecs and human-type influenza hemagglutinin